Delayed Inflammatory Reactions After Hyaluronic Acid Filling of Neck Lines: A Case Report.

The incidence of adverse events after hyaluronic acid filling is gradually increasing. In addition to acute reactions in the early postoperative period, there have been some cases of delayed inflammatory reactions. However, such events are rarely reported in Asia, which may be due to atypical symptoms, long intervals, and misidentification of the product quality. Herein, we present a case in which erythema of the neck appeared three weeks after hyaluronic acid injection into the neck lines and a delayed inflammatory reaction was diagnosed. Watchful waiting was performed, and the erythema subsided spontaneously after two weeks. This case suggests that in patients with a history of hyaluronic acid injections who develop allergic and inflammatory reactions after an interval, it is important to consider whether the reaction is a delayed inflammatory reaction, and if aggressive intervention is necessary.

Structural changes in intercity mobility networks of China during the COVID-19 outbreak: A weighted stochastic block modeling analysis.

This study focuses on a mesoscale perspective to examine the structural and spatial changes in the intercity mobility networks of China from three phases of before, during and after the Wuhan lockdown due to the outbreak of COVID-19. Taking advantages of mobility big data from Baidu Maps, we introduce the weighted stochastic block model (WSBM) to measure and compare mesoscale structures in the three mobility networks. The results reveal significant changes to volume and structure of the intercity mobility networks. Particularly, WSBM results show that the intercity network transformed from a typical core-periphery structure in the normal phase, to a hybrid and asymmetric structure with mixing core-peripheries and local communities in the lockdown phase, and to a multi-community structure with nested core-peripheries during the post-lockdown phase. These changes suggest that the outbreak of COVID-19 and the travel restrictions deconstructed the original hierarchy of the intercity mobility network in China, making the network more locally or regionally fragmented, even at the recovery stage. This study provides new empirical and methodological insights into understanding mobility network dynamics under the impact of COVID-19, helping assess the emergency-induced impact as well as the recovery process of the mobility network.